Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079540 | 0.88 | ALDH1A1 (0.50) | ALDH1A1SOAT1TSHRHSD17B10LMNA | |
| SCHEMBL14991303 | 0.84 | CYP19A1 (0.47) | CYP19A1ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL14991573 | 0.84 | CYP19A1 (0.47) | CYP19A1ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL14991588 | 0.84 | CYP19A1 (0.47) | CYP19A1ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL26393466 | 0.82 | CYP19A1 (0.46) | CYP19A1ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL1078000 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SOAT1TSHRATMTHRB | |
| SCHEMBL1078609 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SOAT1TSHRHPGDATM | |
| SCHEMBL7270086 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SOAT1TSHRHSD17B10LMNA | |
| SCHEMBL29315120 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SOAT1TSHRATMTHRB | |
| SCHEMBL29315096 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SOAT1TSHRHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022279-B1 | NEW CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6310056-B1 | 2-SUBSTITUTED WITH A IMIDAZO(5,1-B)THIAZOLE GROUP; TREATING INFECTIONS, INCLUDING ANTIBIOTIC RESISTANT BACTERIAL INFECTIONS | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1022279-A1 | NEW CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2000-07-26 | — | — | EP | disclosed |