Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834892 | 1.00 | ACE (0.51) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| Serine SCHEMBL6413521 | 0.91 | ACE (0.45) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL28866775 | 0.90 | ACE (0.60) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL3369452 | 0.90 | ACE (0.60) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL2897972 | 0.90 | ACE (0.60) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL497515 | 0.90 | ACE (0.60) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL1221172 | 0.90 | ACE (0.60) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL4669890 | 0.90 | ACE (0.60) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL3780597 | 0.90 | ACE (0.60) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL4669921 | 0.90 | ACE (0.60) | ACELMNAABCB11SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323489-B2 | Proline ester and preparation containing the same for percutaneous administration | TOAEIYO LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | disclosed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | disclosed |
| US-4508727-A | Antihypertensive 2-oxo-imidazolidine derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1985-04-02 | — | — | US | disclosed |
| EP-0095163-A2 | 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1983-11-30 | — | — | EP | disclosed |