Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.55 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87587 | 0.89 | TTR (0.47) | TTRTBK1MAOAKDM4EALDH1A1 | |
| SCHEMBL27408664 | 0.84 | MAOA (0.57) | TTRTBK1MAOAKDM4EALDH1A1 | |
| SCHEMBL27617568 | 0.83 | TTR (0.54) | TTRTBK1MAOAKDM4EALDH1A1 | |
| SCHEMBL11367849 | 0.83 | TTR (0.54) | TTRTBK1MAOAKDM4EALDH1A1 | |
| SCHEMBL1987428 | 0.82 | MAOA (0.62) | TTRTBK1MAOAKDM4EALDH1A1 | |
| SCHEMBL11865624 | 0.82 | TTR (0.44) | TTRTBK1MAOAKDM4EALDH1A1 | |
| SCHEMBL6059629 | 0.79 | ALDH1A1 (0.50) | MAOAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL27697686 | 0.79 | MAOA (0.58) | TTRTBK1MAOAKDM4EALDH1A1 | |
| SCHEMBL32671605 | 0.77 | KDM4E (0.57) | MAOAKDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL11809317 | 0.76 | TTR (0.47) | TTRTBK1MAOAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030138432-A1 | Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs | DRUG INNOVATION & DESIGN, INC. | 2003-07-24 | — | — | US | disclosed |
| EP-1255567-A1 | SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES | Drug Innovation & Design, Inc. (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001036003-A2 | SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES | DRUG INNOVATION & DESIGN, INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| EP-0675145-B1 | Xanthene polymers and copolymers | GEN ELECTRIC (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5504184-A | Xanthene polymers, and copolymers, and method for making | GENERAL ELECTRIC COMPANY (US) | 1996-04-02 | — | — | US | disclosed |
| US-5466777-A | Xanthene polymers, and copolymers, and method for making | GENERAL ELECTRIC COMPANY (US) | 1995-11-14 | — | — | US | disclosed |
| EP-0675145-A2 | Xanthene polymers and copolymers | GENERAL ELECTRIC COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |
| US-4764584-A | Radiation-sensitive polycondensates, their preparation, material coated therewith and the use thereof | CIBA-GEIGY CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |
| US-4714669-A | POLYAMIDES, POLYESTERS, OR POLYESTER AMIDES | CIBA-GEIGY CORPORATION (US) | 1987-12-22 | — | — | US | disclosed |
| US-3957986-A | Antiviral compositions containing bis-basic esters and amides of xanthene and xanthone | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030138432-A1 | Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs | PAICS, ABCB1, ABCG2 | TTR 3149/4885TBK1 2871/4885MAOA 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.