SCHEMBL7270401

SCHEMBL7270401

C=CC(=O)OCc1cccs1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.49
RAB9A P51151 1/20 0.49
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
CYP2C19 P33261 1/20 0.43
THRB P10828 1/20 0.42
POLB P06746 4/20 0.41
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A3 Q01959 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TSHR P16473 1/20 0.39
USP2 O75604 1/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28643500 0.83 THRB (0.51) NPC1RAB9ASLC1A3SLC1A2SLC1A1
SCHEMBL9015298 0.81 TSHR (0.58) NPC1RAB9ACYP2C19THRBPOLB
SCHEMBL28088400 0.80 RAB9A (0.50) NPC1RAB9ASLC1A3SLC1A2SLC1A1
SCHEMBL3633444 0.80 NPC1 (0.59) NPC1RAB9ACYP2C19THRBPOLB
Acrylic Acid SCHEMBL31590930 0.80 THRB (0.51) NPC1RAB9ASLC1A3SLC1A2SLC1A1
SCHEMBL28711480 0.80 NPC1 (0.55) NPC1RAB9ASLC1A3SLC1A2SLC1A1
SCHEMBL28825805 0.79 NPC1 (0.58) NPC1RAB9ACYP2C19THRBPOLB
SCHEMBL28050460 0.79 NPC1 (0.58) NPC1RAB9ACYP2C19THRBPOLB
SCHEMBL9931139 0.79 CYP2C19 (0.47) NPC1RAB9ASLC1A3SLC1A2SLC1A1
SCHEMBL28050508 0.79 NPC1 (0.58) NPC1RAB9ACYP2C19THRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114940654-B Method for synthesizing adiponitrile and adipate compound by reductive dimerization of olefin under photocatalysis 武汉大学 2023-03-10 CN disclosed
CN-114940654-A Method for synthesizing adiponitrile and adipate compound by reductive dimerization of olefin under photocatalysis 武汉大学 2022-08-26 CN disclosed
CN-113264861-B Preparation method of alkyl dithiocarbamate 河南农业大学 2022-08-26 CN disclosed
CN-113264861-A Preparation method of alkyl dithiocarbamate 河南农业大学 2021-08-17 CN disclosed
CN-104768939-A HIGH REFRACTIVE (META)ACRYLATE AND THE METHOD FOR PREPARING THE SAME DAELIM CHEMICAL CO LTD 2015-07-08 CN disclosed
EP-0403159-A2 Imidazolyl-alkenoic acids SMITHKLINE BEECHAM CORPORATION (US) 1990-12-19 EP disclosed