Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903115 | 0.80 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1HCAR2CYP1A2 | |
| SCHEMBL13044441 | 0.78 | ALDH1A1 (0.55) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL27717048 | 0.76 | ALDH1A1 (0.53) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C9 | |
| SCHEMBL20211557 | 0.76 | HCAR2 (0.51) | GSTP1HCAR2LMNAPOLBEGFR | |
| SCHEMBL1070423 | 0.76 | HCAR2 (0.71) | HCAR2LMNAPOLBEGFRBTK | |
| SCHEMBL1070426 | 0.76 | HCAR2 (0.71) | HCAR2LMNAPOLBEGFRBTK | |
| SCHEMBL29063508 | 0.76 | HCAR2 (0.51) | GSTP1HCAR2LMNAPOLBEGFR | |
| SCHEMBL22012721 | 0.75 | CYP1A2 (0.47) | SLC1A3SLC1A2SLC1A1HCAR2LMNA | |
| SCHEMBL14011319 | 0.75 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C9 | |
| SCHEMBL14936845 | 0.75 | HCAR2 (0.50) | GSTP1HCAR2LMNAEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |