Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270631 | 1.00 | MTNR1A (0.51) | MTNR1AMTNR1BDRD4DRD2CA1 | |
| SCHEMBL7272029 | 0.97 | MTNR1A (0.54) | MTNR1AMTNR1BDRD4DRD2CA1 | |
| SCHEMBL7275285 | 0.97 | MTNR1A (0.54) | MTNR1AMTNR1BDRD4DRD2CA1 | |
| SCHEMBL7278332 | 0.88 | MTNR1A (0.46) | MTNR1AMTNR1BDRD4DRD2CA1 | |
| SCHEMBL7279310 | 0.86 | CA1 (0.48) | MTNR1AMTNR1BDRD4DRD2CA1 | |
| SCHEMBL7332063 | 0.86 | MTNR1A (0.63) | MTNR1AMTNR1BDRD4DRD2CA1 | |
| SCHEMBL7332053 | 0.86 | MTNR1A (0.63) | MTNR1AMTNR1BDRD4DRD2CA1 | |
| SCHEMBL7273996 | 0.84 | KMT2A (0.54) | MAPT | |
| SCHEMBL6839554 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BDRD4DRD2CA1 | |
| SCHEMBL8960011 | 0.78 | MTNR1A (0.52) | MTNR1AMTNR1BDRD4DRD2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013760-A | Phenylethylamine derivatives and pharmaceutical use | FISONS PLC (GB) | 1991-05-07 | — | — | US | disclosed |
| EP-0072061-A1 | Amine derivatives, processes for their production and pharmaceutical compositions containing them | FISONS plc (GB) | 1983-02-16 | — | — | EP | disclosed |