Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839554 | 0.85 | MTNR1A (0.56) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL7332053 | 0.82 | MTNR1A (0.63) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL7332063 | 0.82 | MTNR1A (0.63) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL7275285 | 0.81 | MTNR1A (0.54) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL7272029 | 0.81 | MTNR1A (0.54) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL21798809 | 0.79 | MTNR1A (0.49) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL4216627 | 0.79 | CYP1A2 (0.57) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL4656341 | 0.79 | CYP1A2 (0.57) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL4207460 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL7270631 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534536-B1 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON SPA (IT) | 1996-01-31 | — | — | EP | claimed |
| US-5221770-A | PROCESS FOR THE PREPARATION OF 2-AMINO-5,6-DIMETHOXY-TETRALIN | ZAMBON GROUP S.P.A. (IT) | 1993-06-22 | — | — | US | claimed |
| EP-0534536-A2 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON GROUP S.p.A. (IT) | 1993-03-31 | — | — | EP | claimed |
| JP-5201939-A | — | — | None | — | — | JP | disclosed |
| EP-0534536-B1 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON SPA (IT) | 1996-01-31 | — | — | EP | disclosed |
| JP-H05201939-A | PRODUCTION OF 2-AMINO-5,6-DIMETHOXY TETRALIN | ZAMBON GROUP SPA | 1993-08-10 | — | — | JP | disclosed |
| US-5221770-A | PROCESS FOR THE PREPARATION OF 2-AMINO-5,6-DIMETHOXY-TETRALIN | ZAMBON GROUP S.P.A. (IT) | 1993-06-22 | — | — | US | disclosed |
| EP-0534536-A2 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON GROUP S.p.A. (IT) | 1993-03-31 | — | — | EP | disclosed |