Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647151 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL5907764 | 0.83 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL26915243 | 0.78 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL16928460 | 0.73 | TSHR (0.31) | ALDH1A1TSHR | |
| SCHEMBL6347557 | 0.71 | — | — | |
| SCHEMBL7410494 | 0.71 | — | — | |
| SCHEMBL5907754 | 0.70 | — | — | |
| SCHEMBL30656396 | 0.70 | — | — | |
| SCHEMBL18584687 | 0.70 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1061431 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912238-A | REVERSING DRUG RESISTANCE WITH MACROLIDE COMPOUNDS | NOVARTIS AG (CH) | 1999-06-15 | — | — | US | disclosed |
| EP-0427680-B1 | Heteroatoms-containing tricyclic compounds | SANDOZ LTD (CH) | 1995-08-23 | — | — | EP | disclosed |
| US-5352671-A | Heteroatoms-containing tricyclic compounds | SANDOZ LTD. (CH) | 1994-10-04 | — | — | US | disclosed |
| EP-0427680-A1 | Heteroatoms-containing tricyclic compounds | SANDOZ LTD. (CH) | 1991-05-15 | — | — | EP | disclosed |