SCHEMBL3647151

SCHEMBL3647151

CC(O)(O[Si](C)(C)C(C)(C)C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270749 1.00 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL5907764 0.83 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL26915243 0.78 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL16928460 0.73 TSHR (0.31) ALDH1A1TSHR
SCHEMBL6347557 0.71
SCHEMBL7410494 0.71
SCHEMBL5907754 0.70
SCHEMBL30656396 0.70
SCHEMBL18584687 0.70 ALDH1A1 (0.31) ALDH1A1
SCHEMBL1061431 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2176208-B1 PRODRUGS OF CANNABIDIOL, COMPOSITIONS COMPRISING PRODRUGS OF CANNABIDIOL AND METHODS OF USING THE SAME ZYNERBA PHARMACEUTICALS INC (US) 2015-01-21 EP disclosed
US-8293786-B2 Prodrugs of cannabidiol, compositions comprising prodrugs of cannabidiol and methods of using the same ALLTRANZ INC. (US) 2012-10-23 US disclosed
EP-2176208-A1 PRODRUGS OF CANNABIDIOL, COMPOSITIONS COMPRISING PRODRUGS OF CANNABIDIOL AND METHODS OF USING THE SAME AllTranz Inc. (US) 2010-04-21 EP disclosed
US-20090036523-A1 PRODRUGS OF CANNABIDIOL, COMPOSITIONS COMPRISING PRODRUGS OF CANNABIDIOL AND METHODS OF USING THE SAME ALLTRANZ INC. (US) 2009-02-05 US disclosed
WO-2009018389-A1 PRODRUGS OF CANNABIDIOL, COMPOSITIONS COMPRISING PRODRUGS OF CANNABIDIOL AND METHODS OF USING THE SAME ALLTRANZ INC. (US) 2009-02-05 WO disclosed
US-20060149090-A1 Process for producing chain oligolactic acid ester AMATO PHARMACEUTICAL PRODUCTS, LTD. (JP) 2006-07-06 US disclosed
EP-1484311-A1 PROCESS FOR PRODUCING CHAIN OLIGOLACTIC ACID ESTER AMATO PHARMACEUTICAL PRODUCTS, LTD. (JP) 2004-12-08 EP disclosed
US-5912238-A REVERSING DRUG RESISTANCE WITH MACROLIDE COMPOUNDS NOVARTIS AG (CH) 1999-06-15 US disclosed
EP-0427680-B1 Heteroatoms-containing tricyclic compounds SANDOZ LTD (CH) 1995-08-23 EP disclosed
US-5352671-A Heteroatoms-containing tricyclic compounds SANDOZ LTD. (CH) 1994-10-04 US disclosed
EP-0427680-A1 Heteroatoms-containing tricyclic compounds SANDOZ LTD. (CH) 1991-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036523-A1 PRODRUGS OF CANNABIDIOL, COMPOSITIONS COMPRISING PRODRUGS OF CANNABIDIOL AND METHODS OF USING THE SAME CNR2, CNR1, FAAH ALDH1A1 1490/4885TSHR 3837/4885
US-20060149090-A1 Process for producing chain oligolactic acid ester ELOVL1, OSTC, ACSL1 ALDH1A1 403/4885TSHR 4539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.