Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.64 |
| ▸ | ATR | Q13535 | 2/20 | 0.55 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | FADS1 | O60427 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7271004 | 0.99 | SCD (0.62) | SCDATRNPBWR1MAPK14ALDH1A1 | |
| SCHEMBL10960401 | 0.87 | SCD (0.59) | SCDATRNPBWR1FADS1 | |
| SCHEMBL30424949 | 0.81 | NPC1 (0.71) | SCDATRNPBWR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16756458 | 0.81 | NPC1 (0.71) | SCDATRNPBWR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7279613 | 0.80 | SCD (0.52) | SCDATRNPBWR1FADS1 | |
| SCHEMBL10965933 | 0.80 | SCD (0.51) | SCDATRNPBWR1MAPK14ALDH1A1 | |
| SCHEMBL11228706 | 0.80 | ALDH1A1 (0.68) | SCDALDH1A1SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7280780 | 0.79 | NPC1 (0.56) | NPBWR1MAPK14ALDH1A1MAPK11SMN1; SMN2 | |
| SCHEMBL7272031 | 0.77 | PDE5A (0.54) | SCDATRNPBWR1ALDH1A1FADS1 | |
| SCHEMBL7272194 | 0.77 | PDE5A (0.50) | SCDATRNPBWR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904785-A | INOTROPIC AGENTS FOR CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| US-4758574-A | 2-phenylimidazio (4,5-c) pyridines | ELI LILLY AND COMPANY (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0093593-A2 | Pyridine compounds | ELI LILLY AND COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |