Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 5/20 | 0.75 |
| ▸ | DRD3 | P35462 | 5/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.75 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.75 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.75 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.75 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.75 |
| ▸ | HRH1 | P35367 | 1/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.75 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279998 | 0.87 | ADRB2 (0.79) | DRD1DRD3SLC6A2SLC6A3ADRB2 | |
| SCHEMBL28615035 | 0.86 | DRD1 (0.72) | DRD1DRD3SLC6A2SLC6A3ADRB2 | |
| SCHEMBL30350890 | 0.86 | DRD1 (0.72) | DRD1DRD3SLC6A2SLC6A3ADRB2 | |
| SCHEMBL7272756 | 0.86 | DRD1 (0.72) | DRD1DRD3SLC6A2SLC6A3ADRB2 | |
| SCHEMBL7278498 | 0.86 | ADRB2 (1.00) | DRD1DRD3SLC6A2SLC6A3ADRB2 | |
| Dopexamine SCHEMBL29711811 | 0.86 | ADRB2 (1.00) | DRD1DRD3SLC6A2SLC6A3ADRB2 | |
| Dopexamine SCHEMBL122233 | 0.86 | ADRB2 (1.00) | DRD1DRD3SLC6A2SLC6A3ADRB2 | |
| Dopexamine SCHEMBL5605569 | 0.86 | ADRB2 (1.00) | DRD1DRD3SLC6A2SLC6A3ADRB2 | |
| SCHEMBL7272201 | 0.86 | ADRB2 (1.00) | DRD1DRD3SLC6A2SLC6A3ADRB2 | |
| Bromide SCHEMBL7281386 | 0.86 | ADRB2 (0.77) | DRD1DRD3SLC6A2SLC6A3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013760-A | Phenylethylamine derivatives and pharmaceutical use | FISONS PLC (GB) | 1991-05-07 | — | — | US | claimed |
| EP-0072061-A1 | Amine derivatives, processes for their production and pharmaceutical compositions containing them | FISONS plc (GB) | 1983-02-16 | — | — | EP | claimed |
| US-5013760-A | Phenylethylamine derivatives and pharmaceutical use | FISONS PLC (GB) | 1991-05-07 | — | — | US | disclosed |
| EP-0072061-A1 | Amine derivatives, processes for their production and pharmaceutical compositions containing them | FISONS plc (GB) | 1983-02-16 | — | — | EP | disclosed |