Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740543 | 0.80 | GAA (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL11293843 | 0.80 | GAA (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2005549 | 0.77 | NAAA (0.52) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL1319964 | 0.77 | NAAA (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7636739 | 0.75 | EPHX1 (0.53) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7430516 | 0.75 | MGAM (0.44) | MGAMGAASIMGAM2NAAA | |
| SCHEMBL7427174 | 0.72 | MGAM (0.41) | MGAMGAASIMGAM2NAAA | |
| SCHEMBL20954557 | 0.71 | MGAM (0.40) | MGAMGAASIMGAM2NAAA | |
| SCHEMBL20954287 | 0.71 | ALDH1A1 (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6939177 | 0.71 | GAA (0.40) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174131-A2 | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them | FISONS plc (GB) | 1986-03-12 | — | — | EP | disclosed |