SCHEMBL7270974

SCHEMBL7270974

COC(=O)C1=C(C)CS(=O)(=O)[C@H]2[C@@H](Cl)C(=O)N12

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270969 1.00 ELANE (0.67) ELANE
SCHEMBL7351285 0.84 ELANE (0.72) ELANE
SCHEMBL7271999 0.84 ELANE (0.72) ELANE
SCHEMBL7271996 0.84 ELANE (0.72) ELANE
SCHEMBL7349002 0.81 ELANE (1.00) ELANE
SCHEMBL7293070 0.81 ELANE (0.67) ELANE
SCHEMBL7329190 0.81 ELANE (1.00) ELANE
SCHEMBL8670925 0.79 ELANE (0.65) ELANE
SCHEMBL8670924 0.79 ELANE (0.65) ELANE
SCHEMBL7293526 0.76 ELANE (1.00) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0457381-B1 Delta 2-cephem sulphones PHARMACIA SPA (IT) 1996-03-06 EP disclosed
EP-0457381-A2 Delta 2-cephem sulphones PHARMACIA S.p.A. (IT) 1991-11-21 EP disclosed