Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271999 | 1.00 | ELANE (0.72) | ELANE | |
| SCHEMBL7271996 | 1.00 | ELANE (0.72) | ELANE | |
| SCHEMBL7270969 | 0.84 | ELANE (0.67) | ELANE | |
| SCHEMBL7329190 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL7293070 | 0.84 | ELANE (0.67) | ELANE | |
| SCHEMBL7270974 | 0.84 | ELANE (0.67) | ELANE | |
| SCHEMBL7349002 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL7293524 | 0.83 | ELANE (1.00) | ELANE | |
| SCHEMBL7293526 | 0.83 | ELANE (1.00) | ELANE | |
| SCHEMBL9755499 | 0.82 | ELANE (0.50) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356888-A | Elastase inhibitors | FARMITALIA CARLO ERBA (IT) | 1994-10-18 | — | — | US | disclosed |
| EP-0378604-B1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES | ERBA CARLO SPA (IT) | 1994-03-02 | — | — | EP | disclosed |
| EP-0378604-A1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES. | ERBA CARLO SPA (IT) | 1990-07-25 | — | — | EP | disclosed |
| WO-1989010926-A1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-11-16 | — | — | WO | disclosed |