Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351285 | 1.00 | ELANE (0.72) | ELANE | |
| SCHEMBL7271996 | 1.00 | ELANE (0.72) | ELANE | |
| SCHEMBL7270969 | 0.84 | ELANE (0.67) | ELANE | |
| SCHEMBL7329190 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL7293070 | 0.84 | ELANE (0.67) | ELANE | |
| SCHEMBL7270974 | 0.84 | ELANE (0.67) | ELANE | |
| SCHEMBL7349002 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL7293524 | 0.83 | ELANE (1.00) | ELANE | |
| SCHEMBL7293526 | 0.83 | ELANE (1.00) | ELANE | |
| SCHEMBL9755499 | 0.82 | ELANE (0.50) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494914-B1 | 2-SPIROCYCLOPROPYL CEPHALOSPORIN DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LAB INC (CA) | 1998-12-23 | — | — | EP | disclosed |
| EP-0580650-B1 | NOVEL 2-SPIROCYCLOPROPYL 4-ACYLCEPHEMS AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LAB INC (CA) | 1998-07-29 | — | — | EP | disclosed |
| EP-0457381-B1 | Delta 2-cephem sulphones | PHARMACIA SPA (IT) | 1996-03-06 | — | — | EP | disclosed |
| EP-0337704-B1 | Beta-lactam derivatives | PHARMACIA SPA (IT) | 1995-06-14 | — | — | EP | disclosed |
| EP-0580650-A1 | NOVEL 2-SPIROCYCLOPROPYL 4-ACYLCEPHEMS AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES INC. (CA) | 1994-02-02 | — | — | EP | disclosed |
| US-5264430-A | Enzyme inhibitor, antiinflammatory agents, treats emphysema, cystic fibrosis and arthritis | SYNPHAR LABORATORIES, INC. (CA) | 1993-11-23 | — | — | US | disclosed |
| US-5264429-A | Enzyme inhibitor, antiinflammatory agents, treats emphysema, cystic fibrosis and arthritis | SYNPHAR LABORATORIES, INC. (CA) | 1993-11-23 | — | — | US | disclosed |
| US-5258377-A | Elastase inhibitors | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| WO-1992017482-A1 | NOVEL 2-SPIROCYCLOPROPYL 4-ACYLCEPHEMS AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES, INC. (CA) | 1992-10-15 | — | — | WO | disclosed |
| US-5077286-A | Human leukocyte elastase inhibitor | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-12-31 | — | — | US | disclosed |
| EP-0457381-A2 | Delta 2-cephem sulphones | PHARMACIA S.p.A. (IT) | 1991-11-21 | — | — | EP | disclosed |
| WO-1991004977-A1 | NOVEL 2-SPIROCYCLOPROPYL CEPHALOSPORIN SULFONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES, INC. (CA) | 1991-04-18 | — | — | WO | disclosed |
| EP-0337704-A2 | Beta-lactam derivatives | PHARMACIA S.p.A. (IT) | 1989-10-18 | — | — | EP | disclosed |