Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.56 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | METAP1 | P53582 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039619 | 0.85 | DRD2 (0.60) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL630841 | 0.84 | ACHE (0.58) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL23181421 | 0.83 | METAP1 (0.60) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL3587277 | 0.83 | CYP24A1 (0.55) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL22867686 | 0.83 | CYP24A1 (0.55) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL2440274 | 0.83 | CYP24A1 (0.56) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL5753017 | 0.83 | CYP24A1 (0.55) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL7519184 | 0.81 | CYP24A1 (0.54) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| Hydrochloric Acid SCHEMBL1813880 | 0.81 | CYP24A1 (0.54) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL7147602 | 0.80 | CYP24A1 (0.56) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080115-A2 | Hexahydronaphth(1,2-b)-1,4-oxazines, process for their preparation and pharmaceutical formulation containing them | MERCK & CO. INC. (US) | 1983-06-01 | — | — | EP | disclosed |