Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FOS | P01100 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821956 | 0.85 | MEN1 (0.68) | ALDH1A1MEN1KMT2AMAPTFOS | |
| SCHEMBL7821958 | 0.85 | MEN1 (0.68) | ALDH1A1MEN1KMT2AMAPTFOS | |
| SCHEMBL28931550 | 0.83 | AKR1C3 (0.47) | ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9475106 | 0.81 | MEN1 (0.62) | ALDH1A1MEN1KMT2AMAPTFOS | |
| SCHEMBL7421645 | 0.81 | MEN1 (0.62) | ALDH1A1MEN1KMT2AMAPTFOS | |
| SCHEMBL7273129 | 0.81 | MEN1 (0.54) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL11163967 | 0.80 | GAA (0.60) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL3540130 | 0.78 | ALOX5 (0.58) | ALDH1A1MEN1KMT2AMAPTFOS | |
| SCHEMBL10350421 | 0.78 | MEN1 (0.51) | ALDH1A1MEN1KMT2AMAPTFOS | |
| SCHEMBL31483473 | 0.78 | MEN1 (0.51) | ALDH1A1MEN1KMT2AMAPTFOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114273-B1 | NEW PHARMACOLOGICALLY ACTIVE PYRAZOLOPYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1991-11-06 | — | — | EP | disclosed |
| US-4954508-A | HYPOTENSIVE | GRUPPO LEPETIT S.P.A. (IT) | 1990-09-04 | — | — | US | disclosed |
| EP-0114273-A1 | New pharmacologically active pyrazolopyridines | GRUPPO LEPETIT S.p.A. (IT) | 1984-08-01 | — | — | EP | disclosed |