SCHEMBL727139

SCHEMBL727139

O=C(Cl)c1ccc2cc(C(=O)Cl)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
LCK P06239 1/20 0.46
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HPGD P15428 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
EGFR P00533 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
PKM P14618 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
JAK1 P23458 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375279 1.00 CES2 (0.52) CES2CES1LCKALDH1A1KDM4E
SCHEMBL8775402 0.95 LCK (0.48) CES2CES1LCKALDH1A1KDM4E
SCHEMBL1681902 0.92 CES2 (0.50) CES2CES1LCKALDH1A1KDM4E
SCHEMBL1225 0.91 CES2 (0.68) CES2CES1ALDH1A1KDM4EMEN1
SCHEMBL30674399 0.91 CES2 (0.68) CES2CES1ALDH1A1KDM4EMEN1
SCHEMBL7358277 0.91 KDM4E (0.57) CES2CES1ALDH1A1KDM4EMEN1
SCHEMBL3923530 0.89 MEN1 (0.58) CES2CES1LCKMEN1KMT2A
SCHEMBL30988908 0.89 CES2 (0.59) CES2CES1LCKALDH1A1KDM4E
Hydrochloric Acid SCHEMBL5219366 0.89 CES2 (0.65) CES2CES1ALDH1A1KDM4EMEN1
SCHEMBL7608517 0.89 CYP2A6 (0.48) CES2CES1LCKKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4616929-A1 POLYAMIDE COMPOSITE MEMBRANE AND PREPARATION METHOD THEREFOR Wanhua Chemical Group Co., Ltd. (CN) 2025-09-17 EP claimed
US-20250154318-A1 PHTHALIMIDINE- CONTAINING CARDO BISPHENOLS BEARING PENDANT FURYL GROUP AND POLYMERS THEREFROM COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2025-05-15 US claimed
US-12258306-B2 Diamine, polymer and film produced using the same SK INNOVATION CO., LTD. (KR) 2025-03-25 US claimed
WO-2025015778-A1 REVERSE OSMOSIS MEMBRANE PREPARATION METHOD AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2025-01-23 WO claimed
CN-118108661-A Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-05-31 CN claimed
CN-117946392-A Terminal group crosslinked polyimide resin, polyimide film and preparation method thereof 华为技术有限公司 2024-04-30 CN claimed
US-11970592-B2 Window cover film and flexible display panel including the same SK INNOVATION CO., LTD. (KR) 2024-04-30 US claimed
CN-117946391-A Micro-crosslinking polyimide resin, polyimide film and preparation method thereof 华为技术有限公司 2024-04-30 CN claimed
CN-117930589-A Polyimide positive photoresist composition and application thereof 上海泽丰半导体科技有限公司 2024-04-26 CN claimed
US-20240043634-A1 PRECURSOR, POLYMER, OPTICAL FILM COMPRISING POLYMER, AND DISPLAY DEVICE COMPRISING OPTICAL FILM KOLON INDUSTRIES, INC. (KR) 2024-02-08 US claimed
US-4891135-A SOLVENT RESISTANCE HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-02 US claimed
EP-0091778-B1 IMPROVEMENT IN OR RELATING TO AROMATIC POLYAMIDE FILM TEIJIN LIMITED (JP) 1987-12-09 EP claimed
WO-1987007282-A1 PREPARATION OF AROMATIC HETEROCYCLIC POLYMERS THE DOW CHEMICAL COMPANY (US) 1987-12-03 WO claimed
EP-0247856-A2 Preparation of aromatic heterocyclic polymers THE DOW CHEMICAL COMPANY (US) 1987-12-02 EP claimed
US-4539393-A Dimensionally stable poly-m-phenylene isophthalamide film TEIJIN LIMITED (JP) 1985-09-03 US claimed
EP-0041043-B1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF ALKENYL BENZENE OR ALKENYL NAPHTHALENE CIBA-GEIGY AG (CH) 1983-11-09 EP claimed
EP-0091778-A2 Improvement in or relating to aromatic polyamide film TEIJIN LIMITED (JP) 1983-10-19 EP claimed
EP-0040177-B1 PROCESS FOR THE PREPARATION OF BENZENE OR NAPHTHALENE ALKENYL CARBOXYLIC ACID DERIVATIVES CIBA-GEIGY AG (CH) 1983-07-20 EP claimed
US-4335054-A Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 US claimed
US-4335055-A Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12258306-B2 Diamine, polymer and film produced using the same PUF60, DDT, PARG CES2 3141/4885CES1 4850/4885LCK 3273/4885
US-20250154318-A1 PHTHALIMIDINE- CONTAINING CARDO BISPHENOLS BEARING PENDANT FURYL GROUP AND POLYMERS THEREFROM PCBP1, PBRM1, DPYD CES2 2403/4885CES1 3378/4885LCK 761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.