SCHEMBL8775402

SCHEMBL8775402

O=C(Cl)c1ccc2cc3cc(C(=O)Cl)ccc3cc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
CYP2A6 P11509 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
EGFR P00533 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
JAK1 P23458 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL727139 0.95 CES2 (0.52) LCKCES2CES1CYP2A6ALDH1A1
SCHEMBL29375279 0.95 CES2 (0.52) LCKCES2CES1CYP2A6ALDH1A1
SCHEMBL30988908 0.93 CES2 (0.59) LCKCES2CES1ALDH1A1KDM4E
SCHEMBL8156791 0.93 CES2 (0.59) LCKCES2CES1ALDH1A1KDM4E
SCHEMBL1681902 0.92 CES2 (0.50) LCKCES2CES1CYP2A6ALDH1A1
SCHEMBL6345963 0.89 LCK (0.64) LCKCES2CES1CYP2A6ALDH1A1
SCHEMBL30674399 0.86 CES2 (0.68) CES2CES1ALDH1A1KDM4EMEN1
SCHEMBL7358277 0.86 KDM4E (0.57) CES2CES1ALDH1A1KDM4EMEN1
SCHEMBL1225 0.86 CES2 (0.68) CES2CES1ALDH1A1KDM4EMEN1
SCHEMBL7608517 0.84 CYP2A6 (0.48) LCKCES2CES1CYP2A6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP claimed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP claimed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP disclosed
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP disclosed
US-20200407508-A1 METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2020-12-31 US disclosed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN disclosed
WO-2019170529-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2019-09-12 WO disclosed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP disclosed
EP-0641831-B1 Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same DOW CORNING ASIA LTD (JP) 1997-11-12 EP disclosed
US-5464922-A Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same DOW CORNING ASIA LTD. (JP) 1995-11-07 US disclosed
EP-0641831-A1 Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same DOW CORNING ASIA, Ltd. (JP) 1995-03-08 EP disclosed
US-4035344-A Process for preparing ordered aromatic copolyamide urea polymer THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-07-12 US disclosed
US-3960818-A Ordered aromatic copolyamide urea polymer THE FIRESTONE TIRE & RUBBER COMPANY (US) 1976-06-01 US disclosed