Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 9/20 | 0.48 |
| ▸ | PREP | P48147 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264235 | 0.89 | FKBP1A (0.52) | FKBP1APREPACEALDH1A1CYP3A4 | |
| SCHEMBL7273048 | 0.89 | FKBP1A (0.52) | FKBP1APREPACEALDH1A1CYP3A4 | |
| SCHEMBL10932183 | 0.85 | FKBP1A (0.56) | FKBP1APREPACE | |
| SCHEMBL7264272 | 0.84 | ACE (0.52) | FKBP1APREPACEALDH1A1CYP3A4 | |
| SCHEMBL7263794 | 0.83 | FKBP1A (0.52) | FKBP1APREPACEALDH1A1CYP3A4 | |
| SCHEMBL7265463 | 0.82 | CMA1 (0.54) | FKBP1AACEALDH1A1CYP3A4TSHR | |
| SCHEMBL15251734 | 0.82 | ACE (0.56) | FKBP1AACE | |
| SCHEMBL15251733 | 0.82 | ACE (0.56) | FKBP1AACE | |
| SCHEMBL11869876 | 0.82 | CYP3A4 (0.61) | FKBP1APREPACEALDH1A1CYP3A4 | |
| SCHEMBL11869863 | 0.82 | CYP3A4 (0.61) | FKBP1APREPACEALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |