Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122718 | 1.00 | MMP1 (0.40) | MMP1MMP2MMP9MMP12HDAC2 | |
| SCHEMBL27476576 | 0.77 | MMP1 (0.40) | MMP1MMP2MMP9MMP12 | |
| SCHEMBL8319487 | 0.76 | KMT2A (0.55) | MMP1MMP2MMP9MMP12HDAC2 | |
| SCHEMBL8198206 | 0.76 | KMT2A (0.50) | MMP1MMP2MMP9MMP12ELANE | |
| SCHEMBL27318954 | 0.76 | SMN1; SMN2 (0.44) | MMP1MMP2MMP9MMP12ELANE | |
| SCHEMBL23356900 | 0.75 | DPP4 (0.49) | SCN4AELANECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4447785 | 0.75 | DPP4 (0.49) | SCN4AELANECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2016284 | 0.75 | DPP4 (0.49) | SCN4AELANECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8203929 | 0.75 | POLB (0.49) | MMP1MMP2MMP9MMP12ELANE | |
| Hydrochloric Acid SCHEMBL27383606 | 0.75 | MMP1 (0.41) | MMP1MMP2MMP9MMP12HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |