Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596550 | 0.77 | LMNA (0.40) | USP30L3MBTL1 | |
| SCHEMBL3362088 | 0.76 | F2 (0.38) | USP30 | |
| SCHEMBL3362092 | 0.76 | F2 (0.38) | USP30 | |
| SCHEMBL642839 | 0.74 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL9382586 | 0.74 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL5846260 | 0.73 | KMT2A (0.40) | — | |
| SCHEMBL7229706 | 0.73 | POLB (0.42) | — | |
| SCHEMBL2715883 | 0.73 | POLB (0.42) | — | |
| SCHEMBL10610305 | 0.72 | GPR119 (0.36) | USP30GPR119AAK1SSTR4 | |
| SCHEMBL7156656 | 0.72 | HTT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378690-A | Treatment of angiotensin induced hypertension | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0274259-B1 | New renin-inhibitory oligopeptides, their preparaton and their use | SANKYO CO (JP) | 1994-02-16 | — | — | EP | disclosed |
| EP-0274259-A2 | New renin-inhibitory oligopeptides, their preparaton and their use | Sankyo Company Limited (JP) | 1988-07-13 | — | — | EP | disclosed |