Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.61 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272049 | 0.86 | ACE (0.74) | ACEACE2 | |
| SCHEMBL9098688 | 0.86 | ACE (0.74) | ACEACE2 | |
| SCHEMBL33721990 | 0.85 | ACE (0.64) | ACEACE2 | |
| SCHEMBL9069201 | 0.82 | ACE (0.60) | ACEACE2LMNALTA4H | |
| SCHEMBL7383518 | 0.82 | ACE (0.62) | ACEACE2LMNALTA4H | |
| SCHEMBL11268587 | 0.82 | ACE (0.62) | ACEACE2LMNALTA4H | |
| SCHEMBL10768813 | 0.82 | ACE (0.59) | ACEACE2LMNALTA4H | |
| SCHEMBL9068758 | 0.82 | ACE (0.60) | ACEACE2LMNALTA4H | |
| SCHEMBL10768815 | 0.82 | ACE (0.59) | ACEACE2LMNALTA4H | |
| SCHEMBL9069203 | 0.82 | ACE (0.60) | ACEACE2LMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196931-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-12-08 | — | — | WO | disclosed |