Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282368 | 0.93 | SIGMAR1 (0.44) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL7282728 | 0.91 | SIGMAR1 (0.40) | SIGMAR1CCNCCDK8ASAH1CA12 | |
| SCHEMBL7274358 | 0.90 | SIGMAR1 (0.44) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL7283476 | 0.90 | SIGMAR1 (0.45) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL7275605 | 0.89 | NQO2 (0.38) | SIGMAR1 | |
| SCHEMBL7275258 | 0.88 | CA12 (0.41) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL7275517 | 0.88 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL7272287 | 0.87 | SIGMAR1 (0.42) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL7281590 | 0.87 | SIGMAR1 (0.44) | SIGMAR1 | |
| SCHEMBL7280624 | 0.86 | SIGMAR1 (0.45) | SIGMAR1CA1CA2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |