SCHEMBL7272291

SCHEMBL7272291

O=C[C@@H]1CCCN1C(=O)CCCCC(=O)NCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
DPP4 P27487 4/20 0.54
DPP8 Q6V1X1 2/20 0.54
DPP7 Q9UHL4 1/20 0.54
GAA P10253 1/20 0.52
EPHX2 P34913 2/20 0.49
LMNA P02545 1/20 0.48
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
HRH3 Q9Y5N1 1/20 0.46
FAAH O00519 1/20 0.46
FKBP1A P62942 1/20 0.46
HTR1A P08908 1/20 0.45
HTR7 P34969 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7275001 0.98 GAA (0.56) MEN1KMT2ADPP4DPP8DPP7
SCHEMBL7266943 0.93 DPP4 (0.56) MEN1KMT2ADPP4DPP8DPP7
SCHEMBL10509400 0.84 MEN1 (0.57) MEN1KMT2ADPP4NPC1RAB9A
SCHEMBL10509401 0.84 MEN1 (0.57) MEN1KMT2ADPP4NPC1RAB9A
SCHEMBL770456 0.84 MEN1 (0.55) MEN1KMT2ADPP4DPP8DPP7
SCHEMBL10506399 0.83 MEN1 (0.56) MEN1KMT2ADPP4NPC1RAB9A
SCHEMBL10507275 0.83 NPC1 (0.62) MEN1KMT2ADPP4EPHX2SMN1; SMN2
SCHEMBL10507283 0.83 NPC1 (0.62) MEN1KMT2ADPP4EPHX2SMN1; SMN2
SCHEMBL7273329 0.82 L3MBTL1 (0.58) MEN1KMT2ADPP4DPP8DPP7
SCHEMBL7267072 0.81 DPP4 (0.59) DPP4DPP8DPP7EPHX2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268190-A1 Prolinal derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1988-05-25 EP claimed