Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 14/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762620 | 0.88 | CACNA1B (0.51) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7272316 | 0.86 | CACNA1F (0.62) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9617833 | 0.86 | CACNA1F (0.62) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL27286151 | 0.86 | MAPT (0.55) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL4503644 | 0.86 | CACNA1B (0.65) | CACNA1B | |
| SCHEMBL11363662 | 0.85 | CACNA1F (0.67) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7371573 | 0.84 | CACNA1F (0.43) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7266648 | 0.83 | CACNA1C (0.49) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL27785616 | 0.83 | CACNA1B (0.48) | CACNA1BPDE1C | |
| SCHEMBL27763850 | 0.83 | CACNA1B (0.43) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350762-B1 | SELECTIVELY INHIBIT THE ACTION OF N-TYPE CALCIUM CHANNEL; | AJINOMOTO CO., INC. (JP) | 2002-02-26 | — | — | US | disclosed |
| CN-1283187-A | Novel dipydropyridine derivative | AJINOMOTO KK (JP) | 2001-02-07 | — | — | CN | disclosed |
| EP-1043314-A1 | NOVEL DIHYDROPYRIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2000-10-11 | — | — | EP | disclosed |
| CN-1261348-A | Dihydropyridine derivatives | AJINOMTO CO INC (JP) | 2000-07-26 | — | — | CN | disclosed |
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| US-4876254-A | CARDIOVASCULAR DISORDERS, HYPERTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| EP-0287867-A1 | Substituted 5-nitro-1,4-dihydropyridines, method for their preparation and their use | BAYER AG (DE) | 1988-10-26 | — | — | EP | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |
| CN-85101692-A | Prepare method of 3-nitro-dihydro-pyridine and uses thereof | — | 1987-01-24 | — | — | CN | disclosed |