Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267468 | 0.90 | CACNA1B (0.47) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL28762620 | 0.88 | CACNA1B (0.51) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL10664938 | 0.87 | MAPT (0.44) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9617833 | 0.87 | CACNA1F (0.62) | MAPTKMT2AMEN1ALDH1A1CACNA1B | |
| SCHEMBL7272316 | 0.87 | CACNA1F (0.62) | MAPTKMT2AMEN1ALDH1A1CACNA1B | |
| SCHEMBL7435510 | 0.87 | CACNA1B (0.53) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL2849117 | 0.86 | MAPT (0.66) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL2849115 | 0.86 | MAPT (0.66) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7272376 | 0.86 | CACNA1B (0.53) | CACNA1BADORA3CACNA1CPDE1CCACNA1F | |
| SCHEMBL8680780 | 0.84 | ADORA3 (0.67) | MAPTKMT2AMEN1ALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1039583-A | 1,4-dihydropyridine threonine derivatives, preparation method, intermediate and medicinal application | BAYER AG (DE) | 1990-02-14 | — | — | CN | disclosed |