SCHEMBL7272640

SCHEMBL7272640

CCC(Br)C(=O)N1C(=O)N(C)C[C@H]1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACE P12821 19/20 0.62
RIPK1 Q13546 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7271461 0.83 ACE (0.72) ACE
SCHEMBL7272644 0.83 ACE (0.72) ACE
SCHEMBL28752391 0.77 ACE (1.00) ACE
SCHEMBL7263616 0.77 ACE (0.71) ACE
SCHEMBL15123049 0.76 ACE (0.65) ACERIPK1
SCHEMBL31694805 0.74 ACE (0.63) ACERIPK1
SCHEMBL29050322 0.74 ACE (0.63) ACERIPK1
SCHEMBL7380856 0.73 ACE (0.62) ACE
SCHEMBL11347469 0.72 ACE (0.60) ACE
SCHEMBL11196573 0.72 ACE (0.60) ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4508727-A Antihypertensive 2-oxo-imidazolidine derivatives TANABE SEIYAKU CO., LTD. (JP) 1985-04-02 US disclosed
EP-0095163-A2 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition Tanabe Seiyaku Co., Ltd. (JP) 1983-11-30 EP disclosed