SCHEMBL7272644

SCHEMBL7272644

CC(Br)C(=O)N1C(=O)N(C)CC1C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACE P12821 18/20 0.72
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7271461 1.00 ACE (0.72) ACEMAPT
SCHEMBL28752391 0.84 ACE (1.00) ACE
SCHEMBL7272640 0.83 ACE (0.62) ACE
SCHEMBL15123049 0.79 ACE (0.65) ACEMAPT
SCHEMBL29050322 0.78 ACE (0.63) ACE
SCHEMBL31694805 0.78 ACE (0.63) ACE
SCHEMBL7380856 0.77 ACE (0.62) ACE
SCHEMBL11196573 0.76 ACE (0.60) ACE
SCHEMBL11347469 0.76 ACE (0.60) ACE
SCHEMBL7270489 0.74 ACE (0.78) ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0095163-A2 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition Tanabe Seiyaku Co., Ltd. (JP) 1983-11-30 EP disclosed