SCHEMBL29050322

SCHEMBL29050322

CC(=O)N1C(=O)N(C)CC1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACE P12821 8/20 0.63
MAPK1 P28482 1/20 0.45
ATM Q13315 1/20 0.39
POLB P06746 2/20 0.37
RIPK1 Q13546 1/20 0.36
P2RX7 Q99572 4/20 0.34
GAA P10253 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31694805 1.00 ACE (0.63) ACEMAPK1ATMPOLBRIPK1
SCHEMBL15123049 0.86 ACE (0.65) ACEMAPK1ATMRIPK1P2RX7
SCHEMBL29050324 0.81 ACE (0.42) ACEMAPK1ATMPOLBGAA
SCHEMBL28576083 0.79 ACE (0.56) ACERIPK1P2RX7
SCHEMBL30768404 0.78 ACE (0.54) ACEP2RX7
SCHEMBL1636773 0.78 ACE (0.54) ACEP2RX7
SCHEMBL7272644 0.78 ACE (0.72) ACE
SCHEMBL28752391 0.78 ACE (1.00) ACE
SCHEMBL7271461 0.78 ACE (0.72) ACE
SCHEMBL24750151 0.76 ACE (0.40) ACEMAPK1POLBRIPK1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631573-A2 TEAD INHIBITORS Orion Corporation (FI) 2025-10-15 EP disclosed
EP-4323338-B1 TEAD INHIBITORS ORION CORP (FI) 2025-10-08 EP disclosed
EP-4247492-A1 MALT-1 MODULATORS Exscientia Al Limited (GB) 2023-09-27 EP disclosed
CN-116528857-A MALT-1 modulators 艾克斯赛安西娅人工智能有限公司 2023-08-01 CN disclosed
WO-2022106857-A1 MALT-1 MODULATORS Exscientia Limited (GB) 2022-05-27 WO disclosed