Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7309601 | 0.92 | ITGB3 (0.40) | ITGB3ITGA2BALDH1A1SMN1; SMN2GLA | |
| SCHEMBL7284350 | 0.90 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1SMN1; SMN2GLA | |
| SCHEMBL7274168 | 0.90 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1SMN1; SMN2GLA | |
| SCHEMBL7281127 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BALDH1A1F10PRSS1 | |
| SCHEMBL7273817 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1F10PRSS1 | |
| SCHEMBL7281817 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2B | |
| SCHEMBL7282096 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7285404 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8882761 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7275114 | 0.85 | ITGB3 (0.61) | ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |