Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273817 | 0.99 | ITGB3 (0.54) | ITGB3ITGA2BLMNAALDH1A1TPSAB1 | |
| SCHEMBL7281817 | 0.92 | ITGB3 (0.54) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL7284350 | 0.92 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1F10 | |
| SCHEMBL7274168 | 0.92 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7282096 | 0.92 | ITGB3 (0.52) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL7285404 | 0.92 | ITGB3 (0.52) | ITGB3ITGA2BLMNAALDH1A1 | |
| SCHEMBL8882761 | 0.91 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7275114 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BPRSS1 | |
| Hydrochloric Acid SCHEMBL7280862 | 0.90 | ITGB3 (0.43) | ITGB3ITGA2BLMNAALDH1A1TPSAB1 | |
| SCHEMBL7272798 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BLMNAALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |