Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.71 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.39 |
| ▸ | F7 | P08709 | 4/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301919 | 0.92 | ITGB3 (0.72) | ITGB3ITGA2BPRSS1IRAK4PDE4A | |
| Hydrochloric Acid SCHEMBL7284581 | 0.90 | ITGB3 (0.58) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7284962 | 0.87 | ITGB3 (0.74) | ITGB3ITGA2BF2IRAK4 | |
| Fradafiban SCHEMBL380350 | 0.83 | ITGB3 (1.00) | ITGB3ITGA2BF2F10PRSS1 | |
| Fradafiban SCHEMBL8863359 | 0.83 | ITGB3 (1.00) | ITGB3ITGA2BF2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL7273087 | 0.83 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1IRAK4PDE4A | |
| Fradafiban SCHEMBL7280818 | 0.83 | ITGB3 (0.98) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7272827 | 0.81 | ITGB3 (0.69) | ITGB3ITGA2BF2IRAK4 | |
| Hydrochloric Acid SCHEMBL7272734 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BF2IRAK4 | |
| SCHEMBL7280749 | 0.78 | ITGB3 (0.84) | ITGB3ITGA2BF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |