Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.74 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.74 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7272734 | 0.89 | ITGB3 (0.58) | ITGB3ITGA2BF2PLAUST14 | |
| SCHEMBL7301919 | 0.88 | ITGB3 (0.72) | ITGB3ITGA2BIRAK4 | |
| SCHEMBL7272822 | 0.87 | ITGB3 (0.71) | ITGB3ITGA2BF2IRAK4 | |
| Fradafiban SCHEMBL8863359 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2BF2PLAUST14 | |
| Fradafiban SCHEMBL380350 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2BF2PLAUST14 | |
| Fradafiban SCHEMBL7280818 | 0.84 | ITGB3 (0.98) | ITGB3ITGA2BF2PLAUST14 | |
| SCHEMBL7272827 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BF2IRAK4 | |
| Hydrochloric Acid SCHEMBL7273087 | 0.79 | ITGB3 (0.59) | ITGB3ITGA2BIRAK4 | |
| Hydrochloric Acid SCHEMBL7284581 | 0.78 | ITGB3 (0.58) | ITGB3ITGA2BF2IRAK4 | |
| SCHEMBL7277614 | 0.77 | ITGB3 (0.71) | ITGB3ITGA2BIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |