Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | GNPAT | O15228 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SDCBP | O00560 | 1/20 | 0.44 |
| ▸ | SDC2 | P34741 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280980 | 0.94 | ALDH1A1 (0.57) | ALDH1A1GAAKMT2APOLBMEN1 | |
| SCHEMBL7280961 | 0.94 | ALDH1A1 (0.57) | ALDH1A1GAAKMT2APOLBMEN1 | |
| SCHEMBL7280949 | 0.94 | ALDH1A1 (0.57) | ALDH1A1GAAKMT2APOLBMEN1 | |
| SCHEMBL9084021 | 0.90 | ALDH1A1 (0.56) | ALDH1A1GAAKMT2APOLBMEN1 | |
| SCHEMBL9084034 | 0.90 | ALDH1A1 (0.56) | ALDH1A1GAAKMT2APOLBMEN1 | |
| SCHEMBL7281365 | 0.86 | ALDH1A1 (0.59) | ALDH1A1GAAKMT2APOLBMEN1 | |
| SCHEMBL7281322 | 0.86 | ALDH1A1 (0.59) | ALDH1A1GAAKMT2APOLBMEN1 | |
| SCHEMBL7281335 | 0.86 | ALDH1A1 (0.59) | ALDH1A1GAAKMT2APOLBMEN1 | |
| SCHEMBL7281721 | 0.82 | ALDH1A1 (0.54) | ALDH1A1GAAKMT2APOLBMEN1 | |
| SCHEMBL7274235 | 0.82 | ALDH1A1 (0.66) | ALDH1A1GAAKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249223-B1 | NOVEL ANTIHYPERTENSIVE AGENT | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0249223-A2 | Novel antihypertensive agent | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-12-16 | — | — | EP | disclosed |