SCHEMBL7272845

CC(=O)N([C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CNS(=O)(=O)N1CCOCC1)C(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	20/20	0.54

▸	CTSE	P14091	7/20	0.51

▸	CTSD	P07339	6/20	0.49

▸	PGA5	P0DJD9	5/20	0.49

▸	PGC	P20142	2/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7265128	0.89	REN (0.57)	RENCTSECTSDPGA5PGC
SCHEMBL7265403	0.86	REN (0.57)	RENCTSECTSDPGA5PGC
SCHEMBL7320800	0.80	REN (0.77)	RENCTSECTSDPGA5PGC
SCHEMBL7272695	0.78	REN (0.56)	RENPGC
SCHEMBL10513501	0.77	REN (0.50)	RENCTSECTSDPGA5PGC
SCHEMBL10513513	0.77	REN (0.50)	RENCTSECTSDPGA5PGC
SCHEMBL7274996	0.77	REN (0.56)	RENPGC
SCHEMBL7275302	0.77	REN (0.56)	RENPGC
SCHEMBL7266084	0.77	REN (0.56)	RENPGC
SCHEMBL7272703	0.76	REN (0.57)	RENPGC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0264795-A2	Amino acid derivatives	MERCK PATENT GmbH (DE)	1988-04-27	—	—	EP	disclosed