Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.57 |
| ▸ | CTSE | P14091 | 3/20 | 0.54 |
| ▸ | CTSD | P07339 | 2/20 | 0.52 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.52 |
| ▸ | PGC | P20142 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265128 | 0.89 | REN (0.57) | RENCTSECTSDPGA5PGC | |
| SCHEMBL7272845 | 0.86 | REN (0.54) | RENCTSECTSDPGA5PGC | |
| SCHEMBL7320800 | 0.83 | REN (0.77) | RENCTSECTSDPGA5PGC | |
| SCHEMBL7275460 | 0.78 | REN (0.60) | REN | |
| SCHEMBL7275457 | 0.78 | REN (0.60) | REN | |
| SCHEMBL7272695 | 0.77 | REN (0.56) | RENPGC | |
| SCHEMBL8909418 | 0.77 | REN (0.58) | REN | |
| SCHEMBL9800529 | 0.77 | REN (0.58) | REN | |
| SCHEMBL7287419 | 0.76 | REN (0.60) | REN | |
| SCHEMBL7274996 | 0.76 | REN (0.56) | RENPGC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264795-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-04-27 | — | — | EP | disclosed |