Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 7/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263963 | 0.89 | ERAP2 (0.46) | ACE2ACEERAP2ERAP1LNPEP | |
| SCHEMBL7265582 | 0.85 | ACE2 (0.44) | ACE2ACEERAP2ERAP1LNPEP | |
| SCHEMBL7273266 | 0.85 | ACE2 (0.44) | ACE2ACEERAP2ERAP1LNPEP | |
| SCHEMBL7263636 | 0.85 | ACE2 (0.41) | ACE2ACEERAP2ERAP1LNPEP | |
| SCHEMBL7273281 | 0.79 | ERAP2 (0.42) | ACE2ACEERAP2ERAP1LNPEP | |
| SCHEMBL18806512 | 0.78 | FKBP1A (0.61) | ACEPREPFKBP1A | |
| SCHEMBL10343310 | 0.78 | FKBP1A (0.61) | ACEPREPFKBP1A | |
| SCHEMBL7271791 | 0.78 | ACE (0.48) | ACE2ACEERAP2ERAP1LNPEP | |
| SCHEMBL7263815 | 0.78 | ERAP2 (0.45) | ACE2ACEERAP2ERAP1LNPEP | |
| SCHEMBL7264188 | 0.78 | ERAP2 (0.45) | ACE2ACEERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |