Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 12/20 | 0.61 |
| ▸ | PREP | P48147 | 3/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10343310 | 1.00 | FKBP1A (0.61) | FKBP1APREPACEALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11217224 | 0.99 | FKBP1A (0.60) | FKBP1APREPACEALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8040977 | 0.99 | FKBP1A (0.60) | FKBP1APREPACEALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL7263625 | 0.94 | FKBP1A (0.56) | FKBP1APREPALDH1A1CYP3A4TSHR | |
| Trifluoroacetic Acid SCHEMBL28910722 | 0.94 | FKBP1A (0.55) | FKBP1APREPACE | |
| SCHEMBL13018403 | 0.91 | FKBP1A (0.59) | FKBP1APREPACEALDH1A1CYP3A4 | |
| SCHEMBL6788139 | 0.90 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL11940447 | 0.90 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL6788131 | 0.90 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL10523178 | 0.89 | FKBP1A (0.51) | FKBP1AACEALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154594-B1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES LLC (US) | 2023-07-19 | — | — | EP | disclosed |
| US-11266669-B2 | FAP-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2022-03-08 | — | — | US | disclosed |
| US-20210308090-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES LLC (US) | 2021-10-07 | — | — | US | disclosed |
| US-20210275491-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES, LLC | 2021-09-09 | — | — | US | disclosed |
| US-11033525-B2 | Fap-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2021-06-15 | — | — | US | disclosed |
| US-20200297745-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | BACH BIOSCIENCES, LLC | 2020-09-24 | — | — | US | disclosed |
| US-10709722-B2 | FAP-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190275064-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | TRUSTEES OF TUFTS COLLEGE | 2019-09-12 | — | — | US | disclosed |
| US-10245248-B2 | FAP-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2019-04-02 | — | — | US | disclosed |
| US-20170319609-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | BACH BIOSCIENCES, LLC | 2017-11-09 | — | — | US | disclosed |
| US-20170319609-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | BACH BIOSCIENCES, LLC | 2017-11-09 | — | — | US | disclosed |
| US-9737556-B2 | FAP-activated therapeutic agents, and uses related thereto | TRUSTEES OF TUFTS COLLEGE (US) | 2017-08-22 | — | — | US | disclosed |
| US-9737556-B2 | FAP-activated therapeutic agents, and uses related thereto | TRUSTEES OF TUFTS COLLEGE (US) | 2017-08-22 | — | — | US | disclosed |
| US-20170128476-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | BACH BIOSCIENCES, LLC | 2017-05-11 | — | — | US | disclosed |
| US-20170128476-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | BACH BIOSCIENCES, LLC | 2017-05-11 | — | — | US | disclosed |
| US-20170119901-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES, LLC | 2017-05-04 | — | — | US | disclosed |
| US-20170119901-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES, LLC | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11266669-B2 | FAP-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | FKBP1A 263/4885PREP 41/4885ACE 108/4885 |
| US-11033525-B2 | Fap-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | FKBP1A 381/4885PREP 50/4885ACE 319/4885 |
| US-20210275491-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | FAP, FIBP, GOT1 | FKBP1A 381/4885PREP 50/4885ACE 319/4885 |
| US-20210308090-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | FAP, FIBP, GOT1 | FKBP1A 381/4885PREP 50/4885ACE 319/4885 |
| US-20200297745-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | FAP, FIBP, GOT1 | FKBP1A 263/4885PREP 41/4885ACE 108/4885 |
| US-20170128476-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | FAP, FIBP, GOT1 | FKBP1A 329/4885PREP 51/4885ACE 100/4885 |
| US-10709722-B2 | FAP-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | FKBP1A 263/4885PREP 41/4885ACE 108/4885 |
| US-10245248-B2 | FAP-activated therapeutic agents, and uses related thereto | FAP, FIBP, FAH | FKBP1A 589/4885PREP 61/4885ACE 197/4885 |
| US-20190275064-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | FAP, FIBP, GOT1 | FKBP1A 263/4885PREP 41/4885ACE 108/4885 |
| US-20170119901-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | FAP, FIBP, FAH | FKBP1A 589/4885PREP 61/4885ACE 197/4885 |
| US-20170319609-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | FAP, FIBP, GOT1 | FKBP1A 329/4885PREP 51/4885ACE 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.