Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939011 | 0.85 | NOS3 (0.34) | NOS3NOS1NOS2 | |
| SCHEMBL15159201 | 0.63 | NOS3 (0.43) | NOS3NOS1NOS2 | |
| SCHEMBL20173400 | 0.63 | NOS3 (0.43) | NOS3NOS1NOS2 | |
| SCHEMBL2471472 | 0.61 | — | — | |
| SCHEMBL935220 | 0.60 | — | — | |
| SCHEMBL28469091 | 0.59 | LMNA (0.32) | — | |
| SCHEMBL3246655 | 0.59 | CA1 (0.31) | — | |
| SCHEMBL13677496 | 0.59 | NOS3 (0.34) | NOS3NOS1NOS2 | |
| SCHEMBL5950443 | 0.58 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL31555355 | 0.58 | NOS3 (0.43) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108380-B1 | PYRIDO 2,3-D PYRIDIMIN-5-ONES | STERLING DRUG INC. (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0095152-B1 | A PROCESS FOR PREPARING NICOTINONITRILES AND INTERMEDIATES USED THEREIN | STERLING DRUG INC. (US) | 1986-10-22 | — | — | EP | disclosed |
| US-4590194-A | 3-[methyl or dimethyl)amino]-6-(pyridinyl)pyridazines and their cardiotonic use | STERLING DRUG INC. (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0150206-A4 | PYRIDINYL-2-PYRIMIDINAMINES USEFUL AS CARDIOTONICS AND PREPARATION THEREOF. | STERLING DRUG INC (US) | 1986-03-18 | — | — | EP | disclosed |
| EP-0150205-A4 | AD(PYRIDINYL)-2-PYRIMIDINYL BDUREAS USEFUL AS CARDIOTONICS AND PREPARATION THEREOF. | STERLING DRUG INC (US) | 1986-02-20 | — | — | EP | disclosed |
| US-4560753-A | 2-Substituted-pyrido[2,3-d]pyrimidin-5(8H)-ones | STERLING DRUG INC. (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0150205-A1 | AD(PYRIDINYL)-2-PYRIMIDINYL BDUREAS USEFUL AS CARDIOTONICS AND PREPARATION THEREOF | STERLING DRUG INC. (US) | 1985-08-07 | — | — | EP | disclosed |
| EP-0150206-A1 | PYRIDINYL-2-PYRIMIDINAMINES USEFUL AS CARDIOTONICS AND PREPARATION THEREOF | STERLING DRUG INC. (US) | 1985-08-07 | — | — | EP | disclosed |
| EP-0075116-B1 | PROCESS FOR PREPARING 1,2-DIHYDRO-6-METHYL-2-OXO-5-(PYRIDINYL)NICOTINONITRILES | STERLING DRUG INC. (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4512993-A | 4(Or 5)-(pyridinyl)-2-pyrimidinamines and cardiotonic use thereof | STERLING DRUG INC. (US) | 1985-04-23 | — | — | US | disclosed |
| US-4107315-A | 5-(Pyridinyl)-2(1H)-pyridinones | STERLING DRUG INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107167-A | Alkyl α-[3-(pyridyl)-anilinomethylene]acetoacetates | STERLING DRUG INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4086233-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4072746-A | CARDIOTONIC AGENTS | STERLING DRUG INC. (US) | 1978-02-07 | — | — | US | disclosed |
| US-4053475-A | ANTI-ALLERGIC AGENTS | STERLING DRUG INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4032523-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-4018770-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-4008235-A | ANTIALLERGIC | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-4004012-A | 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones | STERLING DRUG INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3992380-A | 5,8-Dihydro-5-oxo-2-(4-or 3-pyridinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acids and esters | STERLING DRUG INC. (US) | 1976-11-16 | — | — | US | disclosed |