Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7276085 | 0.91 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1LMNAPOLB | |
| SCHEMBL7283439 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BPPARD | |
| SCHEMBL7283779 | 0.87 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7283093 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1TMPRSS2 | |
| SCHEMBL7275930 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1TMPRSS2 | |
| SCHEMBL7272750 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BALDH1A1LMNAPOLB | |
| SCHEMBL7275215 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1TMPRSS2 | |
| SCHEMBL7280400 | 0.85 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1LMNAPOLB | |
| SCHEMBL7273299 | 0.85 | ITGB3 (0.52) | ITGB3ITGA2BPPARDPRSS1TMPRSS2 | |
| SCHEMBL7273468 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |