Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275442 | 0.92 | ITGB3 (0.43) | ITGB3ITGA2BPRSS1TMPRSS2HRH3 | |
| SCHEMBL7283093 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1TMPRSS2HRH3 | |
| SCHEMBL7273096 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BPPARDPRSS1 | |
| SCHEMBL7272750 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1TMPRSS2 | |
| SCHEMBL7275930 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1TMPRSS2 | |
| SCHEMBL7273000 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BPPARDPRSS1TMPRSS2 | |
| SCHEMBL7275215 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1TMPRSS2 | |
| SCHEMBL7273468 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL7276387 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1 | |
| Water SCHEMBL8881880 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BPPARDPRSS1TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |