Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281888 | 0.97 | NPY1R (0.42) | NPY1RSIGMAR1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7284620 | 0.93 | SIGMAR1 (0.43) | NPY1RSIGMAR1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7283356 | 0.90 | SIGMAR1 (0.41) | NPY1RSIGMAR1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7275472 | 0.87 | SIGMAR1 (0.41) | NPY1RSIGMAR1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7283478 | 0.86 | SIGMAR1 (0.54) | SIGMAR1CYP3A4LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL7281922 | 0.85 | MAPT (0.38) | CYP3A4CYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL7274726 | 0.85 | SIGMAR1 (0.51) | SIGMAR1CYP3A4LMNANPSR1 | |
| SCHEMBL7275131 | 0.84 | SIGMAR1 (0.51) | SIGMAR1CYP3A4LMNANPSR1 | |
| SCHEMBL7273844 | 0.84 | SIGMAR1 (0.51) | SIGMAR1CYP3A4LMNANPSR1 | |
| SCHEMBL7274594 | 0.84 | SIGMAR1 (0.51) | SIGMAR1CYP3A4LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |