Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275131 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CYP3A4CACNA1GNPSR1HDAC3 | |
| SCHEMBL7273844 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CYP3A4CACNA1GNPSR1HDAC3 | |
| SCHEMBL7274726 | 0.99 | SIGMAR1 (0.51) | SIGMAR1CYP3A4CACNA1GNPSR1HDAC3 | |
| SCHEMBL7283478 | 0.97 | SIGMAR1 (0.54) | SIGMAR1CYP3A4CACNA1GNPSR1HDAC3 | |
| SCHEMBL7276194 | 0.96 | SIGMAR1 (0.47) | SIGMAR1CYP3A4CACNA1GNPSR1HDAC3 | |
| SCHEMBL7273590 | 0.92 | SIGMAR1 (0.51) | SIGMAR1CYP3A4CACNA1GNPSR1HDAC3 | |
| SCHEMBL7282422 | 0.91 | CYP3A4 (0.47) | SIGMAR1CYP3A4CACNA1GNPSR1HDAC3 | |
| SCHEMBL7273173 | 0.89 | CA12 (0.42) | SIGMAR1CYP3A4CACNA1GHDAC3HDAC1 | |
| SCHEMBL7275050 | 0.88 | SIGMAR1 (0.47) | SIGMAR1CYP3A4CACNA1GNPSR1HDAC3 | |
| SCHEMBL7272852 | 0.88 | SIGMAR1 (0.40) | SIGMAR1CYP3A4CACNA1GHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |