SCHEMBL924034

SCHEMBL924034

CS(=O)(=O)OC[C@@H]1CCCC[C@H]1COS(C)(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MMP9 P14780 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4829843 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL17688155 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL2548198 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL14268316 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7273258 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL931109 0.95 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL4144733 0.95 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL927049 0.95 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL12908138 0.92 KDM4E (0.33) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL12238524 0.92 KDM4E (0.33) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3057966-B1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE PROCOS SPA (IT) 2017-07-26 EP claimed
US-9518047-B2 Process for the industrial synthesis of lurasidone PROCOS S.P.A. (IT) 2016-12-13 US claimed
EP-3057966-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE Procos S.p.A. (IT) 2016-08-24 EP claimed
US-20160237077-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE PROCOS S.P.A. (IT) 2016-08-18 US claimed
US-9409899-B2 Process for preparing benzisothiazol-3-yl-piperazin-1-yl-methyl-cyclo hexylmethanisoindol-1,3-dione and its intermediates CADILA HEALTHCARE LIMITED (IN) 2016-08-09 US claimed
WO-2015056205-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE PROCOS S.P.A. (IT) 2015-04-23 WO claimed
EP-4463455-B1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS SUVEN LIFE SCIENCES LTD (IN) 2026-04-29 EP disclosed
US-12391698-B2 Substituted piperidines and piperazines and methods for the treatment of CNS disorders SUVEN LIFE SCIENCES LIMITED (IN) 2025-08-19 US disclosed
US-20250092049-A1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS SUVEN LIFE SCIENCES LIMITED (IN) 2025-03-20 US disclosed
EP-4463455-A1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS Suven Life Sciences Limited (IN) 2024-11-20 EP disclosed
WO-2023135528-A1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS SUVEN LIFE SCIENCES LIMITED (IN) 2023-07-20 WO disclosed
WO-2023135528-A1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS SUVEN LIFE SCIENCES LIMITED (IN) 2023-07-20 WO disclosed
US-20230002349-A1 TRICYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF JD BIOSCIENCE INC. (KR) 2023-01-05 US disclosed
US-20110263847-A1 PROCESS OF A QUATERNARY AMMONIUM SALT DAINIPPON SUMITOMO PHARMA CO, LTD. (JP) 2011-10-27 US disclosed
US-20110263847-A1 PROCESS OF A QUATERNARY AMMONIUM SALT DAINIPPON SUMITOMO PHARMA CO, LTD. (JP) 2011-10-27 US disclosed
US-20110003994-A1 CYCLOALKANE DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. 2011-01-06 US disclosed
US-5780632-A Imide derivatives and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0464846-B1 Imide derivatives, and their production and use SUMITOMO PHARMA (JP) 1998-04-22 EP disclosed
US-5532372-A Imide derivatives, and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) 1996-07-02 US disclosed
EP-0464846-A1 Imide derivatives, and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1992-01-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002349-A1 TRICYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF TPH1, SLC6A4, TPH2 KDM4E 3463/4885USP2 4248/4885ALDH1A1 714/4885
US-12391698-B2 Substituted piperidines and piperazines and methods for the treatment of CNS disorders GRIN2C, SLC1A2, CNR2 KDM4E 3587/4885USP2 3398/4885ALDH1A1 856/4885
US-20250092049-A1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS GRIN2C, CNR2, INA KDM4E 3897/4885USP2 3766/4885ALDH1A1 1577/4885
US-20110003994-A1 CYCLOALKANE DERIVATIVE CNR2, CNR1, OPRK1 KDM4E 3129/4885USP2 1185/4885ALDH1A1 773/4885
US-20110263847-A1 PROCESS OF A QUATERNARY AMMONIUM SALT KAT5, ATP1B2, QARS1 KDM4E 774/4885USP2 785/4885ALDH1A1 3570/4885
US-20160237077-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE REN, DCXR, ADRA1D KDM4E 1985/4885USP2 2336/4885ALDH1A1 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.