Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | TRHR | P34981 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434222 | 0.92 | TRHR (0.37) | TRHR | |
| SCHEMBL7434209 | 0.92 | TRHR (0.37) | TRHR | |
| SCHEMBL7279683 | 0.86 | FNTA (0.33) | TRHRKMT2A | |
| SCHEMBL7271943 | 0.83 | TRHR (0.47) | TRHRKMT2A | |
| SCHEMBL7333406 | 0.82 | TRHR (0.41) | TRHR | |
| SCHEMBL7327791 | 0.82 | TRHR (0.41) | TRHR | |
| SCHEMBL7274429 | 0.79 | KMT2A (0.35) | ACETRHRKMT2A | |
| SCHEMBL7274436 | 0.79 | KMT2A (0.35) | ACETRHRKMT2A | |
| SCHEMBL7434279 | 0.78 | TRHR (0.37) | TRHR | |
| SCHEMBL7434285 | 0.78 | TRHR (0.37) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |