Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRHR | P34981 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274436 | 1.00 | KMT2A (0.35) | KMT2ACAPN1MAPK1ACETSHR | |
| SCHEMBL7271564 | 0.84 | TRHR (0.47) | KMT2ACAPN1TRHRCTSBSTAT3 | |
| SCHEMBL7433935 | 0.80 | UBE2N (0.35) | KMT2ATSHRKDM4EALDH1A1TRHR | |
| SCHEMBL7433941 | 0.80 | UBE2N (0.35) | KMT2ATSHRKDM4EALDH1A1TRHR | |
| SCHEMBL7359544 | 0.80 | TRHR (0.41) | TRHR | |
| SCHEMBL7273365 | 0.79 | ACE (0.34) | KMT2AACETRHR | |
| SCHEMBL7434222 | 0.79 | TRHR (0.37) | TRHR | |
| SCHEMBL7434209 | 0.79 | TRHR (0.37) | TRHR | |
| SCHEMBL7430679 | 0.79 | TRHR (0.46) | KMT2ACAPN1TRHRCTSB | |
| SCHEMBL7273117 | 0.72 | TRHR (0.47) | CAPN1TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |