Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.72 |
| ▸ | CTSK | P43235 | 7/20 | 0.72 |
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188418 | 1.00 | CTSS (0.72) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL5188769 | 1.00 | CTSS (0.72) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL3477448 | 0.92 | CTSS (0.62) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL1255725 | 0.90 | CTSS (0.69) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL2928795 | 0.88 | CTSS (0.78) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL21676277 | 0.88 | CTSS (0.70) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL31633736 | 0.88 | CTSS (0.70) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL8268491 | 0.88 | CTSS (0.57) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL6549566 | 0.88 | CTSS (0.72) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL4382913 | 0.88 | CTSS (0.70) | CTSSCTSKCTSBCTSLHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141460-A2 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2020-07-09 | — | — | WO | disclosed |
| WO-2020141459-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2020-07-09 | — | — | WO | disclosed |
| CN-103951821-A | Polyethylene glycol-supported bis(S)-2-(4'-benzyloxy)-N-methyl ethane-1,2-diamine and preparation method and application thereof | UNIV HUBEI | 2014-07-30 | — | — | CN | disclosed |
| EP-0498665-B1 | Hydroxamic acids derivatives, process for their preparation and use thereof | BRITISH BIOTECH PHARM (GB) | 1996-04-24 | — | — | EP | disclosed |
| WO-1992013831-A1 | HYDROXAMIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-08-20 | — | — | WO | disclosed |
| EP-0498665-A1 | Hydroxamic acids derivatives, process for their preparation and use thereof | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1992-08-12 | — | — | EP | disclosed |