Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | CTSE | P14091 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281729 | 0.83 | REN (0.56) | RENCTSDCTSE | |
| SCHEMBL9512616 | 0.83 | REN (0.61) | RENCTSDCTSE | |
| SCHEMBL10672536 | 0.82 | REN (0.66) | REN | |
| SCHEMBL7334064 | 0.82 | REN (0.57) | RENCTSDCTSE | |
| SCHEMBL7363470 | 0.82 | REN (0.66) | REN | |
| SCHEMBL10777061 | 0.82 | REN (0.62) | RENCTSDCTSE | |
| SCHEMBL7284721 | 0.82 | CTSS (0.55) | RENCTSDCTSE | |
| SCHEMBL7436551 | 0.82 | REN (0.55) | REN | |
| SCHEMBL7326076 | 0.82 | REN (0.51) | RENCTSDCTSE | |
| SCHEMBL7334713 | 0.82 | CTSS (0.50) | RENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491132-A | HYPOTENSIVE AGENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0476515-A1 | New amino acid derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |