Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7272567 | 0.99 | TACR1 (0.50) | TACR1MAPTALDH1A1RECQLPOLB | |
| Hydrochloric Acid SCHEMBL27301243 | 0.99 | TACR1 (0.50) | TACR1MAPTALDH1A1RECQLPOLB | |
| SCHEMBL7336421 | 0.88 | TACR1 (0.53) | TACR1MAPTALDH1A1RECQLPOLB | |
| SCHEMBL7281772 | 0.85 | TACR1 (0.50) | TACR1MAPTALDH1A1RECQLPOLB | |
| SCHEMBL27305186 | 0.82 | TACR1 (0.47) | TACR1MAPTALDH1A1RECQLPOLB | |
| SCHEMBL7272393 | 0.82 | TACR1 (0.47) | TACR1MAPTALDH1A1RECQLPOLB | |
| SCHEMBL7273716 | 0.82 | TACR1 (0.47) | TACR1MAPTALDH1A1RECQLPOLB | |
| SCHEMBL7284790 | 0.80 | OPRK1 (0.48) | TACR1MAPTALDH1A1RECQLPOLB | |
| SCHEMBL7274220 | 0.80 | ALDH1A1 (0.49) | TACR1MAPTALDH1A1RECQLPOLB | |
| SCHEMBL27303428 | 0.80 | ALDH1A1 (0.49) | TACR1MAPTALDH1A1RECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491132-A | HYPOTENSIVE AGENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0476515-A1 | New amino acid derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |